= 2nd MC thrombosed artery - which supplies the entire posterior part of the heart and the posterior 1/3 of the ventricular septum and the entire right ventricle. Thus, the clinical presentation may resemble pheochromocytoma or Kawasaki disease. Fanconi syndrome) or neuropsychiatric symptoms such as emotional lability, memory impairment, and / or insomnia. Other symptoms may include kidney dysfunction (e.g. epinephrine), a person suffering from mercury poisoning may experience profuse sweating, tachycardia (persistently faster-than-normal heart beat), increased salivation, and hypertension (high blood pressure).Īffected children may show red cheeks, nose and lips, loss of hair, teeth, and nails, transient rashes, hypotonia (muscle weakness), and increased sensitivity to light. Due to the body's inability to degrade catecholamines (e.g. Mercury irreversibly inhibits selenium-dependent enzymes (see below) and may also inactivate S-adenosyl-methionine, which is necessary for catecholamine catabolism by catechol-o-methyl transferase.
If pregnancy does occur, the corpus luteum produces hormones until the placenta takes over that role (at about 3 months)Ĭommon symptoms of mercury poisoning include peripheral neuropathy (presenting as paresthesia or itching, burning or pain), skin discoloration (pink cheeks, fingertips and toes), swelling, and desquamation (shedding of skin). If pregnancy does not occur, the corpus luteum degenerates in 10 days, leaving a scar (corpus albicans) The corpus luteum secretes progesterone and estrogen (granulosa) Mittelschmerz - a twinge of pain sometimes felt at ovulationġ-2% of ovulations release more than one secondary oocyte, which if fertilized, results in fraternal twinsĪfter ovulation, the ruptured follicle collapses, granulosa cells enlarge, and along with internal thecal cells, form the corpus luteum (secretes progesterone, inhibin, estrogen - blockading FSH,LH) Occurs when the ovary wall ruptures and expels the secondary oocyte The LH spike stimulates the primary oocyte to complete meiosis I, and the secondary oocyte continues on to metaphase II high estrogen levels have a positive feedback effect on the pituitary, causing a sudden surge of LH Rising estrogen levels inhibit the release of FSH and LH and they accumulate in pituitary The secondary follicle becomes a mature vesicular follicle (Graafian follicle) Theca folliculi (LH - andro) and granulosa cells (FSH, estrogen) produce estrogen The primordial follicle, directed by the oocyte, becomes a primary follicle -> secondary follicle GnRH stimulates the release of FSH and LH which stimulate follicle growth and maturation, and low-level estrogen release Giant cell astrocytoma, renal angiomyolipoma, and cardiac rhabdomyoma]įollicular Phase (Proliferative) = Period of follicle growth (days 1-14) (haphazardly arranged neurons and cells expressing phenotypes intermediate between glia and neurons) Subependymal hamartomas (large astrocytic and neuronal clusters forming [(facial angiofibroma, seizures, intellectual disability)
MTOR activity, leading to increased protein synthesis and impressive Both proteins form aĬomplex that inhibits the mTOR kinase mutations lead to increased
Tuberous sclerosis locus (TSC1) encodes hamartin the more commonly Include angiofibromas, leathery thickenings (shagreen patches), sunungualįibromas, and hypopigmented areas (ash-leaf patches). Pulmonary lymphangioleiomyomatosis can occur cutaneous lesions Retinal glial hamartomas, cardiac rhabdomyomas, and subependymal hamartomas (large astrocytic and neuronal clusters forming Phenotypes intermediate between glia and neurons) cortical tubers (haphazardly arranged neurons and cells expressing Facial angiofibromas, seizures, and mental retardation.